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Ventricular Late Potentials in Myotonic Dystrophy Ann Int Med 115:607-613, Milner,M.R.,et al, 1991 See this aricle in Pubmed Article Abstract A time-domain analysis of the signal-averaged electrocardiograms showed that 75%of patients with myotonic dystrophy met one criterion for the presence of late potentials,67%met two criteria,and 29%met all three criteria.Spectrotemporal mapping in these patients showed markedly abnormal spectral peaks with a mean factor of normality that was significantly lower than that of the normal volunteers;the frequency of electrocardiographic abnormalities approached that seen in patients with known ventricular tachycardia.The presence of late potentials correlated directly with the length of the PR interval and inversely with left ventricular fractional shortening.In our study,the prevalence of late potentials on signal-averaged electrocadiography in patients with myotonic dystrophy approached that seen in cardiac patients with inducible ventricular tachycardia.It is possible that ventricular arrhythmias play a role in the occurrence of sudden death in some patients with myotonic dystrophy.

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(click to filter results - removes previous filter) arrhythmia,cardiac electrocardiogram,abnormal muscular dystrophy muscular dystrophy,cardiovascular changes with myotonia dystrophica sudden death ventricular tachycardia

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